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    • 专利摘要:
    patent summary "method for producing patient specific plaque". The present invention relates to a method of preparing a patient-specific surgical orthopedic implant that includes obtaining a virtual model of the orthopedic implant that is configured to fit a particular tissue body, and virtually designing the holes in the orthopedic implant. orthopedic implant.
    公开号:BR112015005507A2
    申请号:R112015005507
    申请日:2013-09-11
    公开日:2019-12-17
    发明作者:Furrer Andre；Charles Davison Andrew；A Gheorghe Razvan；Zillig Timo
    申请人:Synthes Gmbh；
    IPC主号:
    专利说明:

    Invention Patent Descriptive Report for METHOD TO PRODUCE PATIENT SPECIFIC PLATE. CROSS REFERENCE TO RELATED APPLICATION [001] This application claims the benefit of provisional US patent application No. 61 / 699,938, filed on September 12, 2012, and US patent application No. 13 / 801,244, filed on 13 March 2013, whose reports are incorporated herein in their entirety, as a reference.
    FIELD OF TECHNIQUE [002] The present description relates, in general, to methods and systems for producing orthopedic implants, and more particularly, to methods and systems for manufacturing patient-specific jaw plates.
    BACKGROUND [003] Many surgical procedures involve attaching orthopedic implants, such as jaw plates, to a bone or bone graft. One or more fasteners, such as bone screws, can be used to attach the orthopedic implant to the bone or bone graft. Some orthopedic implants include implant holes that are configured to receive fasteners. As such, these orthopedic implants can be attached to the bone or bone graft by inserting a fastener through each implant hole and into the bone or bone graft. However, it is important that the fasteners do not come into contact with certain areas of the bone. For example, in mandibular reconstruction, fasteners should not come into contact with nerves, teeth, and / or dental implants to prevent damage to nerves, teeth, dental implants or any other apparatus. It is also important that the fasteners do not interfere with each other when inserted through the implant holes of the orthopedic implant. Therefore, it is desirable to adjust the angle of the ori
    2/17 implant holes so that the fasteners do not interfere with each other and do not come into contact with specific portions of the tissue such as nerves and teeth. The location and orientation of each patient's nerves and teeth may vary. Consequently, it is desirable to produce orthopedic implants that are specifically designed for a particular patient for the purpose of adjusting the angle of the implant holes.
    SUMMARY [004] This description relates to methods of preparing a specific orthopedic implant for the patient using, among other things, a computing device that runs computer-aided software. In one embodiment, the method includes one or more of the following steps: (a) obtaining a virtual three-dimensional model of a tissue body; (b) design of a virtual three-dimensional model of an orthopedic implant that includes an implant body so that the virtual three-dimensional model of the orthopedic implant is contoured to fit over a particular portion of the virtual three-dimensional model of the tissue body; and (c) design of at least one hole that extends through the implant body so that at least one hole is positioned or angled with respect to the implant body so that a virtual three-dimensional model of a fastener does not extend into the interior of a predetermined section of the virtual three-dimensional model of the tissue body when the virtual three-dimensional model of the fastener is arranged, at least partially, in at least one orifice.
    [005] In another embodiment, the method includes one or more of the following steps: (a) design of a virtual three-dimensional model of an orthopedic implant that is contoured to fit over a predetermined portion of a virtual three-dimensional model of a body of tissue, the virtual three-dimensional model of the
    3/17 topedic including an implant body; and (b) creation of at least one virtual orifice that extends through the implant body of the virtual three-dimensional model of the orthopedic implant so that at least one virtual orifice is positioned or angled in relation to the implant body so that a three-dimensional model virtual fastener extends into a predetermined section of a virtual three-dimensional model of the tissue body when the virtual three-dimensional model of the fastener is arranged, at least partially, in at least one orifice.
    BRIEF DESCRIPTION OF THE DRAWINGS [006] The above mentioned summary, as well as the detailed description below of the preferred modalities of the application, will be better understood when read together with the attached drawings. For the purpose of illustrating the surgical instruments and methods of the present application, the preferred modalities are shown in the drawings. It should be understood, however, that the application is not limited to specific modalities and methods presented, and reference is made to the claims for this purpose. In the drawings:
    [007] Figure 1A is a perspective view of a mandible and a specific orthopedic implant for the patient that is attached to the mandible, the orthopedic implant defining a plurality of holes, each of the holes configured and sized to receive a fastener;
    Figure 1B is a top transparent view of a portion of the mandible and the orthopedic implant shown in Figure 1 A, showing fasteners inserted through at least some of the holes and inside the mandible;
    Figure 1C is a transparent bottom view of the mandible portion and the orthopedic implant shown in Figure 1B;
    Figure 1D is a cross-sectional view enlarged one by one
    4/17 tion orthopedic implant shown in Figure 1C, taken around section 1D of Figure 1C;
    Figure 2A is a perspective view of the patient-specific orthopedic implant shown in Figure 1 A;
    Figure 2B is a side view of the patient-specific orthopedic implant shown in Figure 2A;
    Figure 2C is a front view of the patient-specific orthopedic implant shown in Figure 2A;
    Figure 2D is an enlarged cross-sectional view of the patient-specific orthopedic implant shown in Figure 2A, taken along section line 2C to 2C of Figure 2C;
    Figure 3A is a perspective view of a patient-specific orthopedic implant according to another embodiment of the present description;
    Figure 3B is a perspective view of a patient-specific orthopedic implant in accordance with yet another embodiment of the present description; and
    Figure 4 shows a method of preparing the patient-specific orthopedic implants shown in Figures 2A to C and 3A to B. DETAILED DESCRIPTION OF THE ILLUSTRATIVE MODALITIES [008] Certain terminology is used in the following description for convenience only and is not limiting. The words left, right, bottom and top designate directions in the drawings to which reference is made. The words proximally and distally refer to and in the opposite direction of, respectively, the surgeon who uses the surgical device. The words, anterior, posterior, superior, inferior and related words and / or phrases designate the preferred positions and orientations in the human body to which reference is made, and they should not be limiting. The terminology includes the words mentioned above, derived from them and words of
    5/17 similar meaning.
    [009] With reference to Figures 1A to C, a surgical system may include a patient-specific orthopedic implant 100 that is configured to be attached to a patient's tissue body 10. The surgical system may also include one or more fasteners 108 that are configured to attach the patient-specific orthopedic implant 100 to the tissue body 10. One or more fasteners 108 can be configured as bone screws 110. Regardless of their configuration , each fastener 108 is configured and sized to be inserted into one of the holes 106 and inside the tissue body 10, in order to fix the patient-specific orthopedic implant 100 to the tissue body 10. The patient-specific orthopedic implant 100 can be contoured to fit over a particular portion of the tissue body 10 of a specific patient. As used here, tissue body 10 may include a patient's bone as a jaw 16. Although the drawings show jaw 16, tissue body 10 may represent other parts of the patient's anatomy such as the jaw.
    [0010] The patient-specific orthopedic implant 100 can be used to attach a first tissue segment 12 of the tissue body 10 to a second tissue segment of the tissue body 10. The first tissue segment 12 can be separated from the second tissue segment for a defect or portion of diseased tissue. The defect can be, for example, a fracture. In this way, the first tissue segment 12 can be separated from the second tissue segment 14 by a fracture. Fixation of the first tissue segment 12 and the second tissue segment 14 can promote healing of the tissue body 10. Therefore, the patient-specific orthopedic implant 100 can support and maintain the first tissue segment 12 in relation to the second tissue segment 13 at the same time as the
    6/17 osteogenesis. Alternatively, patient-specific orthopedic implant 100 can be used to attach a bone graft to the first tissue segment 12 and the second tissue segment 14. In such a case, a diseased portion of the tissue body 10 can be removed from the patient and replaced by bone graft. The orthopedic implant 100 can then be used to secure the bone graft to the first tissue segment 12 and the second tissue segment 14. In particular, the bone graft can separate the first tissue segment 12 from the second tissue segment 14. Thus , the patient-specific orthopedic implant 100 can support and maintain the bone graft in relation to the first tissue segment 12 and the second tissue segment 14.
    [0011] The patient-specific orthopedic implant 100 and several of its components are described in the present invention with reference to the orthogonal direction components. That is, several parts of the orthopedic implant 100 can extend along a longitudinal direction L, a lateral direction A, and a transversal direction T. The transverse direction T can be substantially perpendicular to the lateral direction A and the longitudinal direction L. A Unless otherwise specified in the present invention, the terms lateral, longitudinal, and transverse are used to describe the orthogonal directional components of the various parts of the patient-specific orthopedic implant 100. When the patient-specific orthopedic implant 100 is coupled to the tissue body 10, the transverse direction T extends along the caudal-cranial direction of the patient, the lateral direction A extends along the central lateral direction of the patient, and the longitudinal direction L extends along the anterior direction - posterior of the patient.
    [0012] With reference to Figures 2A to C, the patient-specific orthopedic implant 100 can be configured as a plate
    7/17 bone 102 and includes an implant body 104 that can be partially or entirely produced from any suitable biocompatible material. Suitable biocompatible materials include, but are not limited to, cobalt-chromium-molybdenum (CoCrMo), titanium, and titanium alloys, stainless steel, ceramics, or polymers such as polyether ether ketone (PEEK), polyether ketone ketone (PEKK), and bioresorbable materials. A coating can be added or applied to the implant body 104 to improve physical or chemical properties or to deliver medications. Examples of coatings include a titanium coating sprayed with plasma or hydroxyapatite.
    [0013] The implant body 104 defines an outer implant surface 112 and an opposite inner implant surface 114. The inner implant surface 114 can be spaced from the outer implant surface 112 along an axial direction 116. One Since the implant body 104 may not have a completely planar configuration, the axial direction 116 may be different across different parts of the implant body 104. The thickness of the implant body 104 can be defined from the external implant surface 112 to the inner implant surface 114 along axial direction 116. Consequently, the implant body 104 can define one or more axes of thickness 118 that extend between the inner surface of the implant 114 and the outer surface of the implant 112. The axis thickness 118 can be substantially perpendicular to the internal implant surface 114 and the external implant surface 112. The internal imp surface lante 114 can be contoured to match the contour of a particular external surface of the tissue body 10 so that the patient-specific orthopedic implant 100 can fit only on that particular external surface of the tissue body 10.
    [0014] Patient-specific orthopedic implant 100 defines
    8/17 one or more holes 106 extending through the implant body 104 between the inner implant surface 114 and the outer implant surface 112 (Figure 2A). Each of the holes 106 can be configured and sized to receive one of the fasteners 108 (Figure 1B). In operation, a fastener 108 can be inserted through the hole 106 and into the tissue body 10 to couple the patient-specific orthopedic implant 100 to the tissue body 10. The holes 106 can be an elongated orifice axis 120 that extends between the internal implant surface 114 and the external implant surface 112. The orifice axis 120 can be oriented with respect to the axis of thickness 118 at an angle Θ. In some embodiments, the angle Θ can range from about zero (0) to about fifteen (15) degrees. However, the angle Θ can be greater than fifteen (15) degrees. Holes 106 may have different orifice axes 120 having different angles. For example, some holes 106 can define orifice axes 120 that are oriented at an oblique angle to the thickness axes, whereas other holes 106 can define orifice axes 120 that are substantially parallel to the thickness axis 118. The angle of the holes 106 in relation to the axes of thickness 118 can depend on several factors. For example, the surgeon may wish to orient a specific hole 106 at a specific angle to the thickness axis 118 so that a fastener 108 inserted through that hole 106 does not come into contact with nerves, teeth, or any other desired portion of tissue of the tissue body 10. In addition, the surgeon may wish to orient two or more adjacent holes 106 at specific angles to the thickness axis 118 so that when fasteners 108 are inserted into these holes 108, fasteners 108 will not interfere with each other (see Figure 1 D).
    [0015] The implant body 104 may have internal surfaces of
    9/17 implant 122 corresponding to each hole 106. Each internal implant surface 122 defines one of the holes 106. Some or all of the holes 106 can be threaded. Therefore, some or all of the holes 106 may include internal implant threads 124 that are configured to correspond to external threads of the fastener 108 so that the fastener 108 can be coupled to the implant body 104. Some or all of the holes 106 may not have internal threads.
    [0016] The patient-specific orthopedic implant 100 can be substantially shaped to correspond to the shape of an external contour of the tissue body 10. In the embodiment shown, the patient-specific orthopedic implant 100 can be designed to be coupled to one side of the jaw 16. For this purpose, the implant body 104 may include a first implant portion 126 and a second implant portion 128 that is angularly displaced with respect to the first implant portion 126 (Figure 2A). The first implant portion 126 can be configured to fit an anterior surface of the mandible 16. In addition, the first implant portion 126 can be connected to the second implant portion 128 in an angular displacement. In the embodiment shown, the first implant portion 126 can be displaced with respect to the second implant portion 128 at an oblique angle. The second implant portion 128 can be configured to fit a lateral surface of the jaw 16. The implant body 104 can also include a third implant portion 130 that is angularly displaced with respect to the first implant portion 126 and the second implant portion 128. The third implant portion 130 can be connected to the second implant portion 128 in an angular displacement. In the embodiment shown, the third implant portion 130 can be displaced angularly relative to the second implant portion 128 at an oblique angle. In addition, the third portion
    10/17 of implant 130 can be configured to fit at least a portion of the branch of the mandible 16.
    [0017] Figure 3A shows another embodiment of a patient-specific orthopedic implant 200 that is similar to the patient-specific orthopedic implant 100 described above. The patient-specific implant 200 can be configured as a bone plate 202 and includes an implant body 204 that is produced from a suitable biocompatible material. Suitable biocompatible materials include, but are not limited to, cobalt-chromium-molybdenum (CoCrMo), titanium, and titanium alloys, stainless steel, ceramics, or polymers such as polyether ether ketone (PEEK), polyether ketone ketone (PEKK), and bioresorbable materials. The patient-specific implant 200 may further define a plurality of holes 206 extending through the implant body 204. The holes 206 may be substantially similar to the holes 106 of the patient-specific implant 100 described above. In this way, the holes 206 are configured to receive fasteners 108. The implant body 204 can be designed to fit over most of the jaw 12. For this purpose, the implant body 204 can include a first implant portion 226 and a second implant portion 228 that is angularly displaced with respect to the first implant portion 226. The first implant portion 226 can be configured to fit over at least one portion of the mandible branch 16. In addition, the first implant portion 226 can be connected to the second implant portion 228 at an oblique angle. The second implant portion 228 can be configured to fit a lateral surface of the jaw 16. The implant body 204 may also include a third implant portion 230 that is connected to the second implant portion 228. The third portion of implant implant 230 can be configured to fit an anterior surface of the
    11/17 jaw 16. Additionally, the third implant portion 230 can be angularly displaced with respect to the second implant portion 228. The implant body 204 includes a fourth implant portion 232 that is connected to the third implant portion 230. A fourth implant portion 232 can be configured to fit a lateral surface of the mandible 16. In addition, the fourth implant portion 232 can be angularly displaced with respect to the third implant portion 230. The implant body 204 includes a fifth portion of implant 234 that is connected to the fourth implant portion 232. The fifth implant portion 234 can be configured to fit at least a portion of the mandible branch 16. Additionally, the fifth implant portion 234 can be angularly displaced with respect to to the fourth portion of implant 232. In the orthopedic field, the patient-specific orthopedic implant 200 is called an implant of double angle.
    [0018] Figure 3B illustrates another modality of a specific implant for patient 300. The specific implant for patient 300 can be configured to fit an anterior portion and parts of the two lateral portions of the mandible 16. In the represented embodiment, the patient-specific implant 300 can be configured as a bone plate 302 and includes an implant body 304. patient-specific implant 300 defines holes 306 that extend through implant body 304. holes 306 can be configured to receive fasteners 108. Holes 306 may be substantially similar to holes 106 described above. The implant body 304 includes a first implant portion 326 and a second implant portion 328 that is connected to the first implant portion 326. The first implant portion 326 is configured to fit a lateral portion of the jaw 16 and is angled displaced with respect to the first 326 implant portion.
    12/17 of the implant portion 328 can fit to an anterior surface of the jaw 16. The implant body 304 may also include a third implant portion 330 that is connected to the second implant portion 328. The second implant portion 328 can be angularly displaced with respect to the second implant portion 328 and can be configured to fit a lateral portion of the mandible
    16.
    [0019] Figure 4 illustrates a method for preparing any of the patient-specific orthopedic implants described above. To summarize, this method is described in relation to the patient-specific orthopedic implant 100. However, the method can be used to prepare any of the patient-specific orthopedic implants described above. This method may include some or all of the steps described below. The patient-specific orthopedic implant 100 can be manufactured preoperatively. Before beginning proper surgery, a virtual three-dimensional image of the tissue body 10 is obtained, using any suitable technology. The virtual three-dimensional image of the tissue body 10 can be obtained by scanning the tissue body 10 with the use of a scanning machine 400 which is suitable for scanning anatomical tissue. For example, the virtual three-dimensional image of the jaw 16 can be obtained using the scanning machine 400. The scanning machine 400 can be a computed tomography (CT) scanning machine, a laser scanning machine, an optical scanning machine, a magnetic resonance imaging (MRI) machine, a coordinate measuring machine or any other machine or device capable of scanning the tissue body 10. Specifically, the machine Scanner 400 can be used to scan the tissue body 10. Independent
    13/17 of the scanning methodology employed, a virtual three-dimensional image of the tissue body 10 is obtained. This image includes images of the tunnels that receive the nerves. Consequently, the location of the nerves in the tissue body 10 can be identified.
    [0020] When the virtual three-dimensional image of the tissue body 10 is obtained, the image data obtained by the scanning machine 400 can then be downloaded or transferred to a computing device 402 to create a virtual three-dimensional model of the tissue body 10. The computing device 402 can be local (i.e., in the same general area as the scanning machine 400) or remote to where the image should be transmitted via a network. The computing device 402 includes a processor that is capable of manipulating image data. In addition to the processor, computing device 402 may include a non-transitory computer-readable storage medium that is capable of storing image data. Alternatively, computing device 402 may not include a non-transitory computer-readable storage medium; instead, computing device 402 may be coupled to a non-transitory computer-readable storage medium. If so, computing device 402 can run computer aided design software.
    [0021] A virtual three-dimensional model of an orthopedic implant, such as orthopedic implant 100, can be obtained. The virtual three-dimensional model of the orthopedic implant 100 can be composed of data that can be manipulated by a processor and that can be read by a non-transitory computer-readable medium. These data can be in different formats. For example, the virtual three-dimensional model of the orthopedic implant 100 can include data in an STL (Standard Tessellation Language) format. Despite the data format, the virtual three-dimensional model of the orthopedic implant 100
    14/17 includes data that maps the shape, contour, and size of the orthopedic implant 100. The virtual three-dimensional model of the orthopedic implant 100 can be created virtually on a computer. In the computing device 402 or other computing device, the virtual three-dimensional model of the orthopedic implant 100 is designed so that it is contoured and shaped to fit a particular portion of the virtual three-dimensional model of the tissue body 10. For example, the model virtual three-dimensional orthopedic implant 100 can be shaped and contoured to fit an anterior surface and a lateral surface of the mandible 16. The virtual three-dimensional models of the orthopedic implant 100 and the tissue body 10 can be manipulated using appropriate software , such as software sold under the trademark PROPLAN CMF® with Synthes.
    [0022] The virtual three-dimensional model of the orthopedic implant 100 is then processed to create one or more holes 106. The user, as a surgeon, can determine the angle and position of the holes 106 according to a predetermined surgical plan. Specifically, the virtual three-dimensional model of the orthopedic implant 100 can be manipulated so that the holes 106 are positioned in relation to the implant body 104 so that the fasteners 108 do not extend into a predetermined section of the tissue body 10 when the fasteners are at least partially arranged in the holes 106. For example, the virtual three-dimensional model of the orthopedic implant 100 can be manipulated so that the holes 106 are positioned along the implant body 104 so that the fasteners 108 do not come into contact with nerves or teeth of the tissue body 10. Similarly, the virtual three-dimensional model of the orthopedic implant 100 can be manipulated so that the holes 106 are angled with respect to the implant body 104 so that the fasteners 108 do not enter
    15/17 in contact with nerves, teeth, and / or dental implants of the tissue body 10. Holes 106 can be positioned or aligned so that fasteners 108 do not come into contact with any type of hardware, such as a dental implant. The user can also manipulate the virtual three-dimensional model of the orthopedic implant 100 to adjust the position and / or angulation of the holes 106 so that the fasteners 108 do not come into contact with each other when the fasteners 108 are as illustrated in Figure 1D. In determining the appropriate position and / or angulation of the holes 106 in relation to the implant body 104, the user can select the fasteners 108 with the appropriate length so that the fasteners 108 do not interfere with each other when the fasteners 108 are inserted into the holes 106. It is envisaged that the virtual three-dimensional models of the fasteners 108 can be obtained. The virtual three-dimensional models of the fasteners 108 can be inserted through the holes 108 of the virtual three-dimensional model of the orthopedic implant 100 to determine whether the fasteners 108 extend into the nerves, teeth, or interfere with each other. If the virtual three-dimensional models of the fasteners 108 interfere with nerves, teeth, or with each other, the position or angulation of the holes 108 of the virtual three-dimensional model of the orthopedic implant 100 can be manipulated. It is envisaged that the surgeon can manipulate the virtual three-dimensional model of the orthopedic implant 100 prior to surgery to reduce the amount of time spent in the operating room by adjusting the orthopedic implant 100 so that it fits the particular patient. Once the time in the operating room is reduced, the duration of anesthesia can be reduced as well.
    [0023] When the virtual three-dimensional model of the orthopedic implant 100 is complete, the orthopedic implant 100 can be created using any suitable technology. The three-dimensional model
    16/17 of the complete orthopedic implant 100 can be downloaded or transferred from computing device 402 to a 404 manufacturing machine, such as a CAD / CAM manufacturing machine. The virtual three-dimensional model of the complete orthopedic implant 100 can be transferred or downloaded directly from computing device 402 to fabrication machine 404 or from computing device 402 to another computer and then to fabrication machine 404. Fabrication machine 404 can be a computer numerical control machine (CNC). Suitable software can be used to generate the CNC code from the data representing the virtual three-dimensional model of the orthopedic implant 100. For example, software sold under the trademark SYNOPSIS ™ from CADS GmbH can be used to generate the code of the virtual three-dimensional model of the orthopedic implant 100. The software can generate the CNC code in any suitable programming language. For example, SYNOPSIS or any other suitable software can generate the CNC code in the G code or STEP-NC programming languages. The CNC code can then be downloaded or transferred to the CNC machine so that the CNC machine can manufacture the patient-specific orthopedic implant 100.
    [0024] It is envisaged that the methods described above can be used not only to manufacture the orthopedic implants described in the present invention, but also other orthopedic implants or guide implants. For example, the method described in the present invention can be used to manufacture the bone fixation implant and the osteotomy guide implant that are described in US Patent Application Publication No. 2012/0029574, filed April 1, 2011 , the description of which is incorporated by reference into the present invention. In addition, the methods described in the present invention can be used to
    17/17 manufacture and customize the bone fixation device, bone plate, and reference guide which are described in US Patent Application No. 13 / 426,079 filed on March 21, 2012, the description of which is incorporated by reference.
    [0025] It should be noted that the illustrations and discussions of the modalities shown in the figures are for illustrative purposes only, and should not be considered as limiting the description. The person skilled in the art will realize that the present description includes several modalities. For example, although the present description refers to three-dimensional virtual models, it is envisaged that any of the virtual models in the present description can be two-dimensional. It should be further understood that the features and structures described and illustrated according to one modality can apply to all modalities, as described here, except where otherwise indicated. In addition, it should be understood that the concepts described above with the modalities described above can be used alone or in combination with any of the other modalities described above.
    权利要求:
    Claims (20)
    [1]
    1. Method characterized by the fact that it comprises the steps of:
    obtain a virtual three-dimensional model of a tissue body;
    design, through a software program executed by a computer device, a virtual three-dimensional model of an orthopedic implant that includes an implant body, so that the virtual three-dimensional model of the orthopedic implant is contoured to fit a particular portion of the model virtual three-dimensional tissue body, the implant body being elongated along a longitudinal axis, the implant body including at least one hole that extends along an axis of the hole that is angled in relation to the longitudinal axis of the body of implant;
    manipulate, through the software program, the virtual three-dimensional model of the orthopedic implant to superimpose the particular portion of the virtual three-dimensional model of the tissue body in order to define a manipulated virtual three-dimensional model of orthopedic implant;
    insert, through the software program, a virtual three-dimensional model of a fastener at least partially into at least one hole in the implant body so that the virtual three-dimensional model of the fastener does not extend into a predetermined section of the virtual three-dimensional model obtained from the tissue body, wherein the predetermined section of the virtual three-dimensional model obtained from the tissue body includes a nerve, a tooth, or hardware; and transfer the manipulated virtual three-dimensional model of the orthopedic implant to a manufacturing machine, where the manufacturing machine is configured to build an orthopedic implant
    Petition 870160049649, of September 6, 2016, p. 4/12
    [2]
    2/6 patient specific that corresponds to the manipulated virtual three-dimensional model of the orthopedic implant.
    2. Method, according to claim 1, characterized by the fact that the predetermined section is an intersection with another fastener that extends through the implant body.
    [3]
    3. Method, according to claim 1 or 2, characterized by the fact that the tissue body is a jaw and the obtaining step includes obtaining a virtual three-dimensional model of the jaw.
    [4]
    Method according to any one of claims 1 to 3, characterized by the fact that the tissue body is a jaw and the step of obtaining includes obtaining a virtual three-dimensional model of the jaw.
    [5]
    5. Method according to any one of claims 1 to 4, characterized in that the step of obtaining includes scanning the tissue body using a scanning machine selected from the group consisting of a computed tomography (CT) scanning machine ), a laser scanner, an optical scanner, a magnetic resonance imaging (MRI) machine, and a coordinate measuring machine.
    [6]
    6. Method according to any of claims 1 to 5, characterized by the fact that the at least one orifice is a first orifice, the virtual three-dimensional model of the fastener is a virtual three-dimensional model of a first fastener, and the method further comprises the step of designing a second hole that extends through the implant body so that the second hole is positioned or angled in relation to the implant body so that a virtual three-dimensional model of a second fastener does not come into contact with the three-dimensional model first fastener
    Petition 870160049649, of September 6, 2016, p. 5/12
    3/6 when the virtual three-dimensional models of the first and second fasteners are arranged, at least partially, in the first and second holes of the manipulated virtual three-dimensional model of the orthopedic implant, respectively.
    [7]
    7. Method, according to any of claims 1 to 6, characterized by the fact that it still comprises building the patient's specific orthopedic implant to correspond to the virtual three-dimensional model manipulated of the orthopedic implant using a manufacturing machine.
    [8]
    8. Method, according to claim 7, characterized by the fact that it still comprises generating a CNC code using data that represent the manipulated virtual three-dimensional model of the orthopedic implant and at least one orifice.
    [9]
    9. Method according to claim 7 or 8, characterized by the fact that the construction step includes transferring the CNC code to a CNC machine and building the patient-specific orthopedic implant using the CNC machine.
    [10]
    10. Method according to any one of claims 1 to 9, characterized by the fact that the manipulation step includes coupling the virtual three-dimensional model of the orthopedic implant to the virtual three-dimensional model of the tissue body.
    [11]
    11. Method characterized by the fact that it comprises the steps of:
    to design, through a software program executed by a computer device, a virtual three-dimensional model of an orthopedic implant that is contoured to fit a predetermined portion of a virtual three-dimensional model of a tissue body, the virtual three-dimensional model of the orthopedic implant including an implant body that is elongated along a longitudinal axis, and at least one virtual hole that extends through the color
    Petition 870160049649, of September 6, 2016, p. 6/12
    4/6 implant of the virtual three-dimensional model of the orthopedic implant along an orifice axis that is elongated in relation to the longitudinal axis of the implant body;
    manipulate, through the software program, the virtual three-dimensional model of the orthopedic implant to superimpose the predetermined portion of the virtual three-dimensional model of the tissue body in order to define a manipulated virtual three-dimensional model of orthopedic implant;
    insert, through the software program, a virtual three-dimensional model of a fastener at least partially into at least one virtual hole in the implant body so that the virtual three-dimensional model of the fastener does not extend into a predetermined section of the three-dimensional model virtual obtained from the tissue body, wherein the predetermined section of the virtual three-dimensional model obtained from the tissue body includes a nerve, a tooth, or hardware; and transferring the manipulated virtual three-dimensional model of the orthopedic implant to a manufacturing machine, where the manufacturing machine is configured to build a patient-specific orthopedic implant that corresponds to the manipulated virtual three-dimensional model of the orthopedic implant.
    [12]
    12. Method, according to claim 11, characterized by the fact that it still comprises obtaining the virtual three-dimensional model of the tissue body.
    [13]
    13. Method according to claim 11 or 12, characterized in that the step of obtaining includes scanning the tissue body using a scanner selected from the group consisting of a computed tomography (CT) scanner , a laser scanner, an optical scanner, a resonance imaging machine
    Petition 870160049649, of September 6, 2016, p. 7/12
    5/6 magnetic (MRI) and a coordinate measuring machine.
    [14]
    14. Method according to any one of claims 11 to 13, characterized in that, in the obtaining step, the tissue body is a jaw, and the obtaining step additionally includes scanning the jaw using the machine scanning.
    [15]
    15. Method according to any one of claims 11 to 14, characterized by the fact that it still comprises building a physical orthopedic implant to match the manipulated virtual three-dimensional model of the orthopedic implant using the manufacturing machine.
    [16]
    16. Method, according to claim 15, characterized by the fact that it still comprises generating a CNC code using data that represent the virtual three-dimensional model of the orthopedic implant and at least one virtual hole.
    [17]
    17. Method according to claim 15 or 16, characterized by the fact that the construction step includes transferring the CNC code to a CNC machine.
    [18]
    18. Method according to any of claims 15 to 17, characterized by the fact that the construction step includes building the physical orthopedic implant using the CNC machine.
    [19]
    19. Method according to any one of claims 11 to 18, characterized by the fact that the at least one virtual hole is a first virtual hole, the virtual three-dimensional model of the fastener is a virtual three-dimensional model of a first fastener, and the The method comprises the step of designing a second virtual orifice so that the second virtual orifice is positioned and angled in relation to the implant body, so that a virtual three-dimensional model of a second fastener does not interfere with the virtual three-dimensional model of the first fastener when the modes
    Petition 870160049649, of 09/06/2016, p. 12/12
    6/6 the virtual three-dimensional of the first and second fasteners are arranged, at least partially, in the first and second virtual holes of the manipulated virtual three-dimensional model of the orthopedic implant, respectively.
    [20]
    20. Method according to any one of claims 11 to 19, characterized in that the design step includes obtaining local data that includes information about an angle or position of at least one virtual hole in relation to the implant body.
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    同族专利:
    公开号 | 公开日
    EP2895092A1|2015-07-22|
    IN2015DN01883A|2015-08-07|
    CA2884665C|2021-02-09|
    US10548668B2|2020-02-04|
    JP6469573B2|2019-02-13|
    CA2884665A1|2014-03-20|
    KR102230876B1|2021-03-25|
    EP2895092B1|2018-02-21|
    JP2015529533A|2015-10-08|
    US20140074438A1|2014-03-13|
    CN104619279B|2018-06-01|
    US9411939B2|2016-08-09|
    US20160296290A1|2016-10-13|
    CN104619279A|2015-05-13|
    KR20150056573A|2015-05-26|
    WO2014043210A1|2014-03-20|
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    法律状态:
    2018-03-27| B15K| Others concerning applications: alteration of classification|Ipc: A61B 17/80 (2006.01) |
    2018-11-21| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|
    2019-12-31| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|
    2021-08-10| B06A| Patent application procedure suspended [chapter 6.1 patent gazette]|
    2021-10-13| B350| Update of information on the portal [chapter 15.35 patent gazette]|
    2022-02-01| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|
    优先权:
    申请号 | 申请日 | 专利标题
    US201261699938P| true| 2012-09-12|2012-09-12|
    US13/801,244|US9411939B2|2012-09-12|2013-03-13|Method for producing patient-specific plate|
    PCT/US2013/059226|WO2014043210A1|2012-09-12|2013-09-11|Method for producing patient-specific plate|
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